at this point, I think everybody admits that this thing is going to roll through the population of the United States. What we're basically betting on now is how long that takes and how well that's managed.
Chamath’s claim on 15 March 2020 was that SARS‑CoV‑2 would not be contained in the U.S. but would “roll through the population,” with remaining uncertainty only about the timing and management of that spread. Subsequent data show widespread, population‑level penetration of the virus in the United States, consistent with that prediction. By February 2022, the CDC estimated that about 58% of Americans had antibodies indicating prior SARS‑CoV‑2 infection, including roughly three‑quarters of children. (aha.org) Serosurveys of U.S. adults from August 2021–May 2022 found over 90% had anti‑spike antibodies from vaccination and/or infection, and about 42% had anti‑nucleocapsid antibodies indicating documented past infection, with higher infection prevalence in younger adults. (cdc.gov) Blood‑donor data further show that by July–September 2022, about 96% of donors aged 16+ had SARS‑CoV‑2 antibodies from infection or vaccination, with nearly half having hybrid immunity. (pubmed.ncbi.nlm.nih.gov) These findings, along with repeated national waves of transmission and COVID‑19’s current endemic status in the U.S., demonstrate that the virus did spread broadly through the general population rather than being contained, matching the core substance of the prediction. The quote does not specify an exact timeline or policy details, only that widespread spread was inevitable and that what remained uncertain was speed and management; on that narrower claim, available evidence confirms it was accurate.